Research Area

Pathogen Genomics & AMR

Genomic and molecular investigation of enteric pathogens — including Shigella, Salmonella, Escherichia coli, and Providencia — with emphasis on virulence determinants and antimicrobial resistance.

Scientific questions

Which genetic elements drive virulence and resistance in enteric pathogens?
How do conjugative plasmids disseminate toxin genes and resistance determinants?
What genomic signatures predict clinically relevant pathogen behavior?

Associated publications

Selected prior work by BILSER researchers in this area.

Researcher prior work

A plasmid-mediated type III secretion system associated with invasiveness and diarrheagenicity of Providencia rustigianii

Jayedul Hassan, Atsushi Hinenoya, Noritoshi Hatanaka, Sharda Prasad Awasthi, Goutham Belagula Manjunath, Nahid Rahman, Jyoji Yamate, Shota Nakamura, Daisuke Motooka, Akira Nagita, Shah M. Faruque, Shinji Yamasaki

mBio · 2024

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Researcher prior work

Wild raccoons (Procyon lotor) as a potential reservoir of cytolethal distending toxin-producing Providencia strains in Japan

Okechukwu John Obi, Atsushi Hinenoya, Sharda Prasad Awasthi, Noritoshi Hatanaka, Shah M. Faruque, Shinji Yamasaki

Microbiology Spectrum · 2025

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Researcher prior work

Presence of Functionally Active Cytolethal Distending Toxin Genes on a Conjugative Plasmid in a Clinical Isolate of Providencia rustigianii

Jayedul Hassan, Sharda Prasad Awasthi, Noritoshi Hatanaka, Phuong Hoai Hoang, Akira Nagita, Atsushi Hinenoya, Shah M. Faruque, Shinji Yamasaki

Infection and Immunity · 2023

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Future directions

—Genomic surveillance of antimicrobial resistance in clinical and environmental isolates.
—Characterisation of mobile genetic elements in Bangladeshi pathogen populations.